Journal: American Journal of Physiology - Endocrinology and Metabolism
Article Title: Effect of metformin and flutamide on insulin, lipogenic and androgen-estrogen signaling, and cardiometabolic risk in a PCOS-prone metabolic syndrome rodent model
doi: 10.1152/ajpendo.00018.2018
Figure Lengend Snippet: The non-fasting plasma triglyceride (A), cholesterol (B), ApoB48 (C), and ApoB100 (D) response (AUC and iAUC) to a high-fat meal in control, PCOS-prone control, and PCOS-prone treatment groups. Results are means ± SE, n = 12 animals/group. *, **Values with a common symbol are not statistically different (P < 0.05, ANOVA). Apo, apolipoprotein; AUC, area under the curve; iAUC, incremental AUC; Flut, flutamide; Met, metformin; PCOS, polycystic ovary syndrome.
Article Snippet: The magnitude of the postprandial or non-fasting response of plasma glucose and insulin following the meal, and plasma TG, total cholesterol, ApoB48, and ApoB100 following the high-fat meal, were determined by area under the curve (AUC) analysis software (GraphPad Software, San Diego, CA).
Techniques: